Prednisone and prednisolone are glucocorticoids that are commonly used in veterinary medicine to treat a wide variety of inflammatory conditions such as allergies, skin diseases, and arthritis. They work by suppressing the immune system and reducing inflammation. They are typically used short-term to manage acute conditions or as part of long-term management of chronic conditions. Side effects can include increased thirst and urination, weight gain, and increased risk of infection.